Understanding Inflammation: Unveiling the Hidden Causes and Steps to Overcome Chronic Diseases

Inflammation is a widely discussed topic in the field of medicine. It is believed to be linked to almost every chronic disease known to us, including heart disease, cancer, diabetes, obesity, autism, dementia, and even depression.

The prevalence of other inflammatory diseases such as allergies, asthma, arthritis, and autoimmune diseases is also on the rise. As physicians, we are trained to manage inflammation through the use of aspirin, anti-inflammatory medications like Advil or Motrin, steroids, and increasingly potent immune-suppressing drugs with significant side effects.

However, our training often neglects to address the underlying causes of inflammation in chronic diseases. The true culprits behind these inflammatory conditions are hidden allergens, infections, environmental toxins, an inflammatory diet, and stress.

Autoimmune diseases, in particular, now affect a staggering 24 million people and encompass conditions like rheumatoid arthritis, lupus, multiple sclerosis, thyroid disease, inflammatory bowel disease, and more. Sadly, these conditions are frequently treated with powerful immune-suppressing medications rather than addressing the root cause. It’s akin to taking a lot of aspirin while standing on a tack. The solution lies in removing the tack, not increasing the dosage of aspirin or resorting to stronger immune suppressants.

If we wish to alleviate inflammation in the body, we must identify its source and treat it accordingly. We should focus on addressing the fire, not just the smoke. In the field of medicine, we are often trained to diagnose diseases based on symptoms rather than uncovering their underlying causes.

Functional medicine, an emerging 21st-century paradigm known as systems medicine, encourages us to treat the cause rather than merely managing symptoms. It urges us to ask why a person is sick, not just what disease they have.

I recently participated in a group discussion involving a conventional doctor, a rheumatologist, a patient with an autoimmune disease, and one of my patients who had successfully overcome a complex autoimmune disease by addressing the underlying causes. Unfortunately, the other doctors’ focus remained on suppressing inflammation with medication rather than seeking out and treating the root cause. Functional medicine offers a different approach by helping us understand and address the true causes of inflammation instead of relying on temporary solutions. The current practice of medicine is akin to removing the battery from a smoke detector while a fire engulfs your home.

Autoimmune conditions share a common biochemical process: an uncontrolled immune response, also known as systemic inflammation, which leads to the body attacking its own tissues.

When my patient shared how he cured his autoimmune disease by identifying and eliminating the causes of inflammation in his diet and environment, it was dismissed as a “spontaneous remission.” In the face of a groundbreaking medical case, the other doctors showed little curiosity and quickly dismissed the information as mere anecdotes.

The patient in question, a hard-working 46-year-old father of three, was once so inflamed that his daily functioning was severely impaired. However, by addressing the underlying causes of his inflammation, he now enjoys vibrant health, relishing life with his children and fully capable of caring for them.

Stories like these (which I have shared in my blogs, books, and on television) are not mere anecdotes but rather a significant guiding force pointing us in the right direction to find answers to our health issues.

In today’s blog post, I will delve into the concept of autoimmunity, explain how inflammation spirals out of control, discuss some of the underlying causes of these inflammatory fires within the body, and provide you with nine practical steps to cool the flames of inflammation and overcome conditions ranging from allergies to arthritis, and more.

Autoimmunity Unveiled: Understanding the Epidemic of Allergies, Asthma, and Autoimmune Disorders

Autoimmune disorders are on the rise, affecting millions of people worldwide. Conditions like rheumatoid arthritis, lupus, multiple sclerosis, and celiac disease, among others, fall under the umbrella of autoimmune diseases. At their core, these conditions share a common biochemical process: a malfunctioning immune response that leads to systemic inflammation and the body mistakenly attacking its own tissues.

Normally, your immune system acts as a defense mechanism, distinguishing between friend and foe. However, in cases of autoimmunity, the immune system becomes confused and directs its attack towards your joints, brain, thyroid, gut, skin, or even your entire body. This confusion arises due to molecular mimicry, where cells mistakenly mimic certain molecules.

Conventional approaches often struggle to identify the underlying cause of autoimmunity. Functional medicine, on the other hand, provides a roadmap to pinpoint the specific triggers that lead to immune system confusion. Interestingly, autoimmune disorders are predominantly found in developed countries. In contrast, individuals in impoverished nations or those who grew up on farms with extensive animal exposure are less prone to these inflammatory disorders. This suggests that environmental factors and early immune system training play significant roles.

Autoimmune diseases impose a substantial health burden, ranking as the eighth leading cause of death among women. On average, these conditions shorten patients’ lifespans by eight years. The economic impact is also significant, with annual healthcare costs totaling $120 billion, nearly double that of cancer. Conventional treatments, while helpful for symptom management, can often cause undesirable side effects and long-term complications.

However, there is a different approach to addressing autoimmune conditions. In this article, we will share a compelling story that illustrates an alternative perspective—one that aims to treat the root cause of the disease rather than merely managing symptoms. Let us delve deeper into the realm of autoimmunity and discover a path towards effective healing.

Unraveling the Mystery of Autoimmunity: A Journey to Healing

John ‘s path to recovery was far from easy. He endured a frustrating maze of doctor visits, receiving various diagnoses but finding little relief for his escalating health issues. As a diligent professional, he was once robust and thriving, until inflammatory conditions invaded his life. Chronic sinus and prostate infections plagued him, leading to a barrage of antibiotic treatments.

In a cruel twist, severe chest pains landed John  in the emergency room, where doctors discovered swollen lymph nodes and prematurely suspected lymphoma, a form of cancer. For three agonizing weeks, he grappled with despair, only to learn that his affliction was an autoimmune disease. However, identifying the specific autoimmune disease remained elusive for the perplexed doctors.

A battery of abnormal blood tests revealed low white blood cell and platelet counts, elevated levels of auto-antibodies attacking his own tissues, heightened immunoglobulin levels, and autoimmune thyroid disease. Yet, no definitive label could be affixed to John ‘s condition.

In the midst of his turmoil, John  encountered a beacon of hope — functional medicine. Embracing this innovative approach, which explores the underlying causes and imbalances in chronic diseases, I embarked on a quest to unveil the truth behind John ‘s symptoms. Through simple inquiries and diligent investigation, I uncovered a host of triggers: toxins, allergens, and infections, all fueling the flames of inflammation.

John ‘s extensive antibiotic use had disrupted his gut flora, paving the way for yeast overgrowth. Fungus and yeast ran rampant throughout his body, manifesting between his toes, on his toenails, in sensitive areas, and even his scalp. Additionally, he harbored Helicobacter pylori bacteria in his gut, suffered from leaky gut syndrome, and experienced adverse reactions to various foods, including dairy and gluten. His occupation exposed him to toxins, resulting in high levels of mercury accumulation. Chronic sinus infections further compounded his distress.

With a comprehensive plan in place, we embarked on a journey of restoration. I addressed the yeast overgrowth with anti-fungal agents and tackled the H. pylori infection using antibiotics. We eliminated his food allergies, repaired his compromised gut, and initiated a thorough detoxification of heavy metals. Simultaneously, we nurtured his immune system with vital nutrients, including zinc, fish oil, vitamin D, herbs, and probiotics. A clean, whole-foods, allergen-free, and anti-inflammatory diet became his foundation for healing.

During his subsequent follow-up, John ‘s remarkable progress astounded us both. Anticipating modest improvements, I was taken aback when he declared that he felt fantastic.

“What about the fatigue?” I inquired.

“My energy is exceptional,” he responded.

“And the bloating and gas?”


“The reflux?”


“How about your sinuses and chronic phlegm?”

“All clear.”

“And your memory and concentration problems?”

“Vastly improved.”

Remarkably, he shed 15 pounds in the process.

Confirming his transformation, John ‘s laboratory results mirrored his newfound vitality. White cell counts normalized, and immune markers significantly subsided.

John’s story epitomizes the triumph of functional medicine—a groundbreaking paradigm that unravels health issues at their core, targeting underlying causes instead of relying solely on symptom-suppressing medications.

If you are grappling with an autoimmune disease, it is crucial to embrace a comprehensive approach that delves into the root causes and empowers you to take control of your well-being.

Nine Essential Steps for Healing Autoimmune Disease: Taking Charge of Your Health

Are you ready to take back control of your health and conquer autoimmune disease? I’ve got a game plan that will guide you towards vibrant well-being. Let’s dive into the nine crucial steps that will set you on the path to recovery:

Seek out the hidden culprits: Don’t let infections lurk in the shadows. Work with a knowledgeable doctor to identify and treat any underlying yeast, viral, bacterial, or Lyme infections that may be fueling your autoimmune condition.

Unmask hidden food allergens: Take charge of your diet by uncovering any hidden food allergies. Consider IgG food testing and give The Yes No Food List Diet a try—an effective protocol specifically designed to eliminate most common food allergens.

Investigate celiac disease: Request a simple blood test to check for celiac disease. Any doctor can perform this test, and it will provide valuable insights into your condition.

Combat heavy metal toxicity: Don’t let heavy metals wreak havoc on your immune system. Get tested for heavy metal toxicity, as metals like mercury can contribute to the development of autoimmune disorders.

Restore gut health: Heal your gut, heal your body. Discover the strategies outlined in my blog on irritable bowel syndrome to restore balance and harmony to your gut.

Embrace immune-supportive nutrients: Arm yourself with powerful nutrients that can naturally calm your immune response. Incorporate fish oil, vitamin C, vitamin D, and probiotics into your daily regimen.

Move your body: Regular exercise is a natural anti-inflammatory. Engage in physical activity that suits your abilities and preferences, as it will contribute to the reduction of inflammation.

Find solace in deep relaxation: Combat the detrimental effects of stress on your immune system. Explore the therapeutic benefits of practices like yoga, deep breathing exercises, biofeedback, or soothing massages to promote relaxation.

You have the tools at your disposal to embark on this healing journey. Follow these nine steps, address the underlying causes of your condition, and witness the transformation unfold. Let the vibrant health you deserve become your reality once again.

Take charge of your health and overcome autoimmune disease within your reach. Gundry Health offers a comprehensive solution that includes four lab tests per year, a personalized Yes No food list, convenient food logging, and the ability to monitor all your health data through our user-friendly web platform or mobile app. Don’t wait any longer to embark on your journey towards optimal health. Visit gundryhealth.com today and seize this great opportunity to start living a healthier, more vibrant life. Your well-being awaits!


The Gundry Health platform helps members improve gut health using integrated lab testing, lab reviews and disease guidance.